About the Synthetic Yeast Resource Hub

The Synthetic Yeast Resource Hub hosts a number of resources to aid the international collaboration to build the world's first synthetic eukaryotic genome. It will also allow researchers to request Sc2.0 strains and plasmids from the Sc2.0 UK Genome Engineering Resource (SUGER).


The Sc2.0 project aims to replace the Saccharomyces cerevisiae genome with a chemically synthesised alternative version. The synthetic sequence has been designed to incorporate several engineered features that will increase the stability of the genome whilst introducing new elements to aid future biological and biotechnological research. More information on the project can be found here.


SUGER is currently collecting and curating strains and plasmids from the international Sc2.0 consortium. Once synthetic yeast chromosomes are published, they will become available to be requested by the wider research community. For any enquiries regarding SUGER, please contact

Collaborators and Supporters

This work is being done by the Ellis Lab and collaborators at The Centre for Synthetic Biology and Innovation (CSynBI) at Imperial College, working with researchers at The University of Edinburgh and the University of Cambridge. This work is supported by the BBSRC and the EPSRC.

Overview of This Website

The purpose of this website is two-fold: to assist any interested parties in utilising the synthetic yeast project, and to act as a centralised resource for those involved in the synthetic yeast project. Here you can:

Materials and methods

Read and download the lab protocols used by imperial during the project.


Browse the wildtype and the published, designed synthetic sequences. Registered users will also be able to see non-published sequences.

Workflow Tracker

Communicate your progress with the synthetic yeast project. Only available to registered in users.


Converse with other teams in an organised and archived manner. Only available to registered in users.


Register to gain access to the restricted content of this site


Take a look at the synthetic genomes summer school